Low-Density/High-Density Liquid Phase Transition for Model Globular Proteins
نویسندگان
چکیده
منابع مشابه
Low-density/high-density liquid phase transition for model globular proteins.
The effect of molecule size (excluded volume) and the range of interaction on the surface tension, phase diagram, and nucleation properties of a model globular protein is investigated using a combination of Monte Carlo simulations and finite temperature classical density functional theory calculations. We use a parametrized potential that can vary smoothly from the standard Lennard-Jones intera...
متن کاملPhase behaviour of a simple model of globular proteins
A simple model of globular proteins which incorporates anisotropic attractions is proposed. It is closely related to models used to model simple hydrogen-bonding molecules such as water. Theories for both the fluid and solid phases are presented, and phase diagrams calculated. The model protein exhibits a fluidfluid transition which is metastable with respect to the fluid-solid transition for m...
متن کاملA density-driven first-order phase transition in liquid sulfur
First-order phase transitions are characterized by a discontinuous first derivative of the Gibbs free energy, so that volumes and entropies are discontinuous. Such transitions are common in the crystalline state, but extremely rare in liquid substances and experimentally evidenced in only one pure element, phosphorus. Here we report combined in-situ Raman scattering, X-ray diffraction and densi...
متن کاملExactly Soluble Model for Nuclear Liquid-Gas Phase Transition
Thermodynamical properties of nuclear matter undergoing multifragmentation are studied within a simplified version of the statistical model. An exact analytical solution has been found for the grand canonical ensemble. Excluded volume effects are taken into account in the thermodynamically self-consistent way. In thermodynamic limit the model exhibits a first order liquid-gas phase transition w...
متن کاملPhase behaviour of disordered proteins underlying low density and high permeability of liquid organelles.
Many intracellular membraneless organelles form via phase separation of intrinsically disordered proteins (IDPs) or regions (IDRs). These include the Caenorhabditis elegans protein LAF-1, which forms P granule-like droplets in vitro. However, the role of protein disorder in phase separation and the macromolecular organization within droplets remain elusive. Here, we utilize a novel technique, u...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Langmuir
سال: 2010
ISSN: 0743-7463,1520-5827
DOI: 10.1021/la904487z